https://phys.org/nanotech-news/bio-medicine en-us The latest science news on nanobiology, nano medicine, nanotechnology, nanoscience, and nanotech. Exhaled breath contains chemical clues to what's going on inside the body, including diseases like lung cancer. And devising ways to sense these compounds could help doctors provide early diagnoses—and improve patients' prospects. In a study in ACS Sensors, researchers report developing ultrasensitive nanoscale sensors that in small-scale tests distinguished a key change in the chemistry of the breath of people with lung cancer. November is Lung Cancer Awareness Month. https://phys.org/news/2024-11-ultrasensitive-nanoscale-sensors-lung-cancer.html Bio & Medicine Wed, 06 Nov 2024 11:41:03 EST news650115661 Researchers from the IBB-UAB have developed a new class of nanostructures capable of trapping and neutralizing large quantities of the SARS-CoV-2 virus particles, both in liquid solutions and on the surface of materials. https://phys.org/news/2024-11-nanoparticles-neutralize-large-amounts-sars.html Bio & Medicine Nanomaterials Wed, 06 Nov 2024 10:58:14 EST news650113090 Tumors often contain areas of oxygen-deficient tissue that frequently withstand conventional therapies. This is because the drugs applied in tumors require oxygen to be effective. An international research team has developed a novel mechanism of action that works without oxygen: polymeric incorporated nanocatalysts target the tumor tissue selectively and switch off the glutathione that the cells need to survive. https://phys.org/news/2024-10-nanocatalyst-tumors-oxygen.html Bio & Medicine Thu, 31 Oct 2024 14:16:29 EDT news649602985 Researchers at the Terasaki Institute for Biomedical Innovation (TIBI) have developed a revolutionary injectable granular filler that could transform the way diabetic wounds are treated, potentially improving patient outcomes. The study, published in ACS Nano, introduced an innovative approach using specialized porous dermal fillers that accelerate tissue healing and regeneration. https://phys.org/news/2024-10-porous-nanofibrous-microspheres-diabetic-wound.html Bio & Medicine Thu, 31 Oct 2024 14:15:53 EDT news649602949 In recent years, bio-medical engineers have been developing promising techniques that could help diagnose diseases or precisely target specific regions inside the human body. Among these promising therapeutic strategies are methods that rely on the use of nanoparticles (NPs), tiny particles between 1 and 100 nm in size. https://phys.org/news/2024-10-precise-delivery-nanoparticles-lung-caveolae.html Bio & Medicine Thu, 31 Oct 2024 07:50:02 EDT news649511395 The efficient use of cellulose—the primary plant scaffold and a major natural building block—could address many issues associated with petroleum-based polymers across various industries. In the search for more sustainable uses of cellulose, Lithuanian scientists have developed a production method for a nanofibrous cellulose matrix, which has the potential to replace non-renewable industrial even in biomedical applications. https://phys.org/news/2024-10-eco-friendly-nanofibrous-cellulose-matrix.html Bio & Medicine Nanomaterials Wed, 30 Oct 2024 15:09:04 EDT news649519741 In a recent study, an international research team with significant involvement from MedUni Vienna has investigated how nanoplastic particles deposited in the body affect the effectiveness of antibiotics. https://phys.org/news/2024-10-nanoplastics-effectiveness-antibiotics.html Bio & Medicine Wed, 30 Oct 2024 09:43:32 EDT news649500205 Researchers at the Terasaki Institute for Biomedical Innovation have developed a novel nanoparticle-based therapy for obesity treatment, as reported in a recent study published in ACS Nano. The innovative approach targets inflammatory cells in adipose tissue, modulating the immune system and promoting fat tissue browning. The research addresses the growing global obesity epidemic and the limitations of current treatment options. https://phys.org/news/2024-10-nanoparticle-based-approach-inflammatory-cells.html Bio & Medicine Tue, 29 Oct 2024 13:56:23 EDT news649428980 In the fight against antibiotic resistance, a new technology developed at Chalmers University of Technology, in Sweden, can be of great importance when, for example, hip and knee implants are surgically inserted. By heating up small nanorods of gold with near-infrared light (NIR), the bacteria are killed, and the surface of the implant becomes sterile. The researchers are now presenting a new study that increases the understanding of how the gold rods are affected by light and how the temperature in them can be measured. https://phys.org/news/2024-10-gold-nanorod-technology-fry-bacteria.html Bio & Medicine Nanomaterials Tue, 29 Oct 2024 11:45:34 EDT news649421129 Patients with late-stage cancer often have to endure multiple rounds of different types of treatment, which can cause unwanted side effects and may not always help. https://phys.org/news/2024-10-implantable-microparticles-cancer-therapies.html Bio & Medicine Mon, 28 Oct 2024 16:04:19 EDT news649350255 In a laboratory set-up simulating the human stomach and intestine, researchers at the University of Amsterdam have explored the fate of plastic nanoparticles during gastrointestinal digestion. In their paper published in the October issue of Chemosphere, they report how a range of model plastic nanoparticles interact with digestive enzymes and form agglomerates. https://phys.org/news/2024-10-laboratory-simulation-smaller-nanoparticles-subject.html Bio & Medicine Nanomaterials Mon, 28 Oct 2024 15:48:19 EDT news649349294 Researchers at the University of Ottawa have made a breakthrough in heart disease diagnostics. They have developed a new type of contrast agent for a medical imaging technique called intravascular optical coherence tomography (IV-OCT). This new agent, made from gold superclusters (AuSC), could improve doctors' ability to diagnose heart conditions. https://phys.org/news/2024-10-gold-standard-cardiology-imaging-nanoparticles.html Bio & Medicine Mon, 28 Oct 2024 11:40:29 EDT news649334414 There are billions of tiny packets of cellular material called extracellular vesicles (EVs) that are produced by cells and released into each person's blood, saliva, and other bodily fluids. EVs contain invaluable information, such as proteins and genetic material, from their original cell, which can provide insight about the status of the body. Scientists have been trying to leverage EVs for their diagnostic and therapeutic potential but have struggled to do so in a fast and cost-effective way. https://phys.org/news/2024-10-rapid-liquid-biopsy-method-capture.html Bio & Medicine Mon, 28 Oct 2024 11:23:03 EDT news649333381 A new framework bridges a gap in understanding RNA therapeutics by linking the structure of lipid nanoparticles to immune response. It can help scientists and engineers expand the use of RNA medicines beyond vaccines to other therapeutic applications. https://phys.org/news/2024-10-advancing-drug-delivery-framework-links.html Bio & Medicine Fri, 25 Oct 2024 12:06:03 EDT news649076761 A new study shows that a biomedical tool can successfully deliver genetic material to edit faulty genes in developing fetal brain cells. The technology, tested in mice, might have the potential to stop the progression of genetic-based neurodevelopmental conditions, such as Angelman syndrome and Rett syndrome, before birth. https://phys.org/news/2024-10-unique-mrna-delivery-method-faulty.html Bio & Medicine Thu, 24 Oct 2024 15:08:05 EDT news649001282 Researchers from the University of Waterloo have developed a new technology that can hold an entire course of antibiotics in one tiny dose and deliver on demand just the right amount of medication that a particular patient needs to fight an infection. https://phys.org/news/2024-10-nanomedicine-advances-precise-antibiotic-doses.html Bio & Medicine Thu, 24 Oct 2024 11:54:03 EDT news648989641 Exploiting the remarkable capability of viruses to transport gene therapies past what until now has been a circulatory roadblock is at the heart of a University of Alberta-led discovery that promises to re-energize the field of genetic medicine. https://phys.org/news/2024-10-drug-delivery-circulatory-roadblock-gene.html Bio & Medicine Wed, 23 Oct 2024 14:32:03 EDT news648912721 A research team, affiliated with UNIST has developed nanoparticles that effectively treat acute myeloid leukemia (AML), offering the potential to reduce side effects while enhancing therapeutic efficacy by selectively targeting and eliminating leukemia cells. https://phys.org/news/2024-10-nanoparticle-technology-destruction-leukemia-cancer.html Bio & Medicine Tue, 22 Oct 2024 10:54:04 EDT news648813242 One of the pressing problems that the world faces in the era of climate change is how to grow enough healthy food to meet the increasing global population, even as soil contamination rises. Research recently published in Nature Food by an international team of scientists led by the University of Massachusetts Amherst, Guangdong University of Technology, and Central South University of Forestry and Technology, has shown that nutrients on the nanometer scale can not only blunt some of the worst effects of heavy metal and metalloid contamination, but increase crop yields and nutrient content. https://phys.org/news/2024-10-nano-nutrients-blunt-effects-soil.html Bio & Medicine Nanomaterials Tue, 15 Oct 2024 16:13:04 EDT news648227581 Researchers have unveiled a novel approach to tackle obesity by targeting fat absorption in the small intestine. The cutting-edge nanoparticle system, engineered to deliver therapeutic molecules directly to the digestive tract, has shown significant potential to prevent diet-induced obesity. The work is published in the journal Advanced Science. https://phys.org/news/2024-10-nanoparticle-therapy-fat-absorption-combat.html Bio & Medicine Sun, 13 Oct 2024 18:00:01 EDT news647855006 Novel magnetic nanodiscs could provide a much less invasive way of stimulating parts of the brain, paving the way for stimulation therapies without implants or genetic modification, MIT researchers report. https://phys.org/news/2024-10-magnetoelectric-nanodiscs-remote-brain-implants.html Bio & Medicine Fri, 11 Oct 2024 05:00:02 EDT news647793238 A classical way to image nanoscale structures in cells is with high-powered, expensive super-resolution microscopes. As an alternative, MIT researchers have developed a way to expand tissue before imaging it—a technique that allows them to achieve nanoscale resolution with a conventional light microscope. https://phys.org/news/2024-10-expansion-technique-image-nanoscale-cells.html Bio & Medicine Fri, 11 Oct 2024 05:00:02 EDT news647773944 Inflammation of the arteries is a primary precursor and driver of cardiovascular disease—the No. 1 killer of people in the United States. This inflammation is associated with the buildup of dangerous plaque inside the arteries. Advanced treatments are needed to target this inflammation in patients. Michigan State University researchers have tested a new nanoparticle nanotherapy infusion that precisely targets inflammation and activates the immune system to help clear out arterial plaque. https://phys.org/news/2024-10-nanotherapy-artery-inflammation-cardiovascular-disease.html Bio & Medicine Thu, 10 Oct 2024 16:46:04 EDT news647797562 Micelles are spherical molecular structures usually formed by amphiphilic molecules with block structure, which contain both hydrophilic and hydrophobic parts. The hydrophobic tails of these molecules cluster together to form a core, while the hydrophilic heads face outward, creating a protective shell. This structure allows micelles to encapsulate hydrophobic substances within their core and disperse them in a water-based environment. https://phys.org/news/2024-10-micelles-effective-dye-drug-dispersion.html Bio & Medicine Nanomaterials Wed, 09 Oct 2024 16:29:56 EDT news647710187 Opioid drugs are highly effective at relieving pain but come with severe drawbacks. Their side effects range from dizziness to potentially fatal respiratory depression. Their illegal use contributes to nearly half a million deaths worldwide each year. https://phys.org/news/2024-10-nanobody-capable-limiting-side-effects.html Bio & Medicine Wed, 09 Oct 2024 11:28:01 EDT news647692073 Imagine a world where your own immune cells are transformed into cancer-fighting superheroes. This is the promise of CAR-T cell therapy, a groundbreaking treatment that's already saving lives. https://phys.org/news/2024-10-platform-combines-graphene-oxide-antibodies.html Bio & Medicine Tue, 08 Oct 2024 11:08:05 EDT news647604481 In a significant advancement for point-of-care medical diagnostics, a team of researchers from UCLA has introduced a deep learning-enhanced, paper-based vertical flow assay (VFA) capable of detecting cardiac troponin I (cTnI) with high sensitivity. The innovative assay holds the potential to democratize access to rapid and reliable cardiac diagnostics, particularly in resource-limited settings. https://phys.org/news/2024-10-paper-based-sensor-rapid-cardiac.html Bio & Medicine Sun, 06 Oct 2024 12:37:06 EDT news647437014 A group led by Prof. Horacio Cabral has discovered a new method to construct protein complex-based therapeutics. https://phys.org/news/2024-10-polymeric-cloak-stabilizes-cytokine-complex.html Bio & Medicine Fri, 04 Oct 2024 10:04:31 EDT news647255066 A new way of diagnosing lung cancer with a blood draw is 10 times faster and 14 times more sensitive than earlier methods, according to University of Michigan researchers. https://phys.org/news/2024-10-microchip-captures-exosomes-faster-sensitive.html Bio & Medicine Thu, 03 Oct 2024 16:00:34 EDT news647190029 The oral cavity is home to a rich ecosystem of microorganisms that are found in both healthy and diseased states. In the area of dental restoration, highly specialized materials are used to fulfill specific functions so that the patient recovers their dental structures, masticatory and phonetic functions and even enjoys improved aesthetics. https://phys.org/news/2024-10-scientists-silver-nanoparticlebased-hygienic-resin.html Bio & Medicine Thu, 03 Oct 2024 09:43:15 EDT news647167391